Two cases of hemichorea-hemiballism with nonketotic hyperglycemia: a new point of view |
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| Authors: | Carla Battisti Francesca Forte Elisa Rubenni Maria Teresa Dotti Anna Bartali Paola Gennari Antonio Federico Alfonso Cerase |
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| Affiliation: | (1) Operative Unit of Neurology and Neurometabolic Diseases, Policlinico “Le Scotte”, University of Siena, V.le Bracci, 2, 53100 Siena, Italy;(2) Section of Radiology, Department of Orthopedics, Radiology and Otolaryngology, School of Medicine, University of Siena, Siena, Italy;(3) USL 7, Siena, Italy;(4) Unit of Diagnostic and Therapeutic Neuroradiology and InterDepartmental Center of Magnetic Resonance, Policlinico “S.Maria alle Scotte”, Azienda Ospedaliera Universitaria Senese, Siena, Italy |
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| Abstract: | Hemichorea-hemiballism (HCHB) is an usually continuous, nonpatterned, involuntary movement disorder caused by basal ganglia dysfunction, commonly due to a vascular lesion, described in nonketotic hyperglycemic patients. Particular computed tomography and magnetic resonance imaging findings have been described. The pathogenic mechanism of chorea arising during hyperglycemia and the nature of neuroimaging findings are unclear. In this paper we describe two elderly women with onset of HCHB during a hyperglycemic episode. The symptoms persisted in one of them after recovery of normal glycemia. The pathophysiological mechanism of the disease is discussed in the light of clinical and neuroradiological follow-up. |
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| Keywords: | Hemichorea-hemiballism Nonketotic hyperglycemia Diabetes mellitus Magnetic resonance imaging |
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