Inhibitory effects of stilbenes in Sophora moorcroftiana BENTH ex BAKER on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro |
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| Authors: | Toda Shizuo Shirataki Yoshiaki |
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| Affiliation: | Department of Pharmaceutical Science, Kansai College of Oriental Medicine, 2-11-1 Wakaba, Kumatori, Sen-nan, Osaka 590-0482, Japan. toda@kansai.ac.jp |
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| Abstract: | We present the results of an in vitro investigation of the inhibitory effects of sophorastilbene A and (+)-alpha-viniferin isolated from Sophora moorcroftiana BENTH ex BAKER on copper ion-induced protein oxidative modification. They inhibited copper-induced protein oxidative modification. The order of these stilbenes and mannitol as a hydroxyl radical scavenger was sophorastilbene A > (+)-alpha-viniferin > mannitol. |
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| Keywords: | copper protein oxidative modification Sophora moorcroftiana sophorastilbene A (+)‐α‐viniferin |
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