| 64层螺旋CT全肝灌注模式成像在肝细胞癌中的初步应用 |
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| 引用本文： | 梁文,唐海亮,全显跃,谢玉茹,虞春堂,慕革非,杨建明,黄志平.64层螺旋CT全肝灌注模式成像在肝细胞癌中的初步应用[J].中国医学影像技术,2007,23(5):707-710. |
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| 作者姓名： | 梁文 唐海亮 全显跃 谢玉茹 虞春堂 慕革非 杨建明 黄志平 |
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| 作者单位： | 南方医科大学附属珠江医院影像中心,广东 广州,510282 |
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| 摘 要： | 目的利用64层螺旋CT全肝灌注模式观察肝细胞癌(HCC)的CT灌注特征以及在各种灌注图像上的影像表现。方法搜集32例经临床或手术病理证实诊断为HCC患者并以10例正常肝脏作为对照分析。用双筒高压注射器经肘前静脉以5ml/s的速率注入非离子型对比剂(370mgI/ml)和生理盐水,通过肝脏CT灌注软件得出TDC及HAP、HPP、TLP等灌注彩图,并分别测定相应的灌注参数值以评价正常肝脏与HCC的血流动力学状态。结果①正常肝实质TDC形态动脉期上升缓慢,门静脉期上升较快并达峰值,曲线走行自然;而HCC的TDC呈速升型,在动脉期迅速上升并在脾峰值附近达峰值,曲线峰值明显前移,而后可维持平衡或较快下降;②HCC组HAP、HPI明显高于正常组,HAP、HPI值分别为(46.6±16.6)ml/(min.100mg),(84.0±13.1)%,与正常对照有显著性差异(HAP:t=4.32,P<0.01;HPI:t=11.3,P<0.01);HCC组HAP、HPI值明显高于远处肝组织,二者统计学上亦有显著差异(HAP:t=2.08,P<0.05;HPI:t=4.8,P<0.01);③边缘模糊处瘤灶HPP>边缘清晰处瘤灶HPP,两者间统计学上有显著差异(t=9.52,P<0.01)。结论64层螺旋CT全肝灌注模式成像克服了以往灌注成像的不足,简单实用,具有一定的优势。能直观反映肝脏整体及HCC内部的血流灌注特征,从而为HCC的诊断、鉴别诊断和治疗提供重要的指导价值。
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| 关 键 词： | 肝肿瘤 CT灌注成像 全肝灌注 |
| 文章编号： | 1003-3289（2007）05-0707-04 |
| 收稿时间： | 2007-01-14 |
| 修稿时间： | 2007-01-142007-04-08 |
Preliminary application of 64-slice spiral CT whole-liver perfusion in hepatocellular carcinoma |
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| LIANG Wen,TANG Hai-liang,QUAN Xian-yue,XIE Yu-ru,YU Chun-tang,MU Ge-fei,YANG Jian-ming and HUANG Zhi-ping.Preliminary application of 64-slice spiral CT whole-liver perfusion in hepatocellular carcinoma[J].Chinese Journal of Medical Imaging Technology,2007,23(5):707-710. |
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| Authors: | LIANG Wen TANG Hai-liang QUAN Xian-yue XIE Yu-ru YU Chun-tang MU Ge-fei YANG Jian-ming and HUANG Zhi-ping |
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| Institution: | Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China;Imaging Center, the Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China |
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| Abstract: | |
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| Keywords: | Liver neoplasms CT perfusion imaging Whole-liver perfusion |
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