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Graphic analysis of contraction-distension isotherms for pulmonary surfactant monolayers
Authors:B R Mogilevich  G V Ostrovskaya  I A Khasabova  V A Berezovskii  V K Rybal'chenko
Institution:(1) Laboratory of Membranology, T. I. Shevchenko University, Kiev;(2) Department of Clinical Pathophysiology, R. E. Kavetskii Institute of Experimental Pathology, Oncology, and Radiology, Ukrainian National Academy of Sciences, Kiev
Abstract:A new method for analyzing the surface-active properties of pulmonary surfactants is proposed, based on calculating a “local stability index” and then plotting this index as a function ofS/S o, whereS o andS are, respectively, the initial and contracted areas of the surfactant monolayer formed at the interface. The course of the curves thus obtained allows for reasonably precise and easy comparisons of alterations in the surface-active properties of pulmonary surfactants in response to different factors acting on the body. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N o 10, pp 370–372, October, 1995 Presented by B. I. Tkachenko, Member of the Russian Academy of Medical Sciences
Keywords:pulmonary surfactants                      surface-active properties                      surface tension                      analytical methods
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