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Age-Dependent Effects of Electroconvulsive Therapy on Memory
Authors:Zervas Iannis M.  Calev Avraham  Jandorf Lina  Schwartz Joseph  Gaudino Elizabeth  Tubi Nurith  Lerer Bernard  Shapira Baruch
Affiliation:State University of New York at Stony Brook, USA.
Abstract:We examined the relation between age and recovery of memory functions after electroconvulsive therapy (ECT). In a group of patients 20-65 years of age, older depressed patients treated with ECT experienced more severe and longer lasting memory deficits than did younger patients. Testing conducted 24-72 h after a course of ECT showed more severe deficits in older patients for verbal and visuospatial anterograde memory, and for retrograde memory. The difference between younger and older subjects was marginal at 1 month follow-up, seen only in differences in verbal anterograde memory. At 6 months follow-up, no difference in memory test scores between older and younger patients was observed. Older patients are more vulnerable to cognitive effects of ECT, and these effects last longer.
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