| Ghrelin与消化系统的关系研究进展 |
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| 引用本文： | 王燕,董蕾.Ghrelin与消化系统的关系研究进展[J].国际消化病杂志,2006,26(3):180-183. |
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| 作者姓名： | 王燕 董蕾 |
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| 作者单位： | 西安交通大学第二医院消化内科,710004;西安交通大学第二医院消化内科,710004 |
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| 摘 要： | Ghrelin是新近发现的一种脑肠肽,1999年由日本科学家Kojima从大鼠胃中分离出来,是生长激素促分泌素受体(GHSR)的天然配体,故又称生长素。Ghrelin可调节生长激素(GH)和其他激素的释放,调节能量代谢,抑制肿瘤细胞增殖,影响心血管功能。近来研究发现,Ghrelin与胃动素(motilin)及消化系统关系密切,此文就这方面的研究进展作一综述。
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| 关 键 词： | Ghrelin 胃动素 胃排空 MMC 幽门螺杆菌 |
| 收稿时间： | 2005-03-02 |
| 修稿时间： | 2005年3月2日 |
Progress of Ghrelin and its relationship with the digestive system |
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| WANG Yan,DONG Lei.Progress of Ghrelin and its relationship with the digestive system[J].International Journal of Digestive Disease,2006,26(3):180-183. |
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| Authors: | WANG Yan DONG Lei |
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| Abstract: | Ghrelin is a new brain-gut peptide found in the stomach of rats in 1999. As the natural ligand of somatotropin secretogogue receptor, it has many activities including: modulating the secretion of growth hormone and other hormones, regulating energy metabolism, inhibiting tumor cell proliferation, as well as influencing cardiovascular function. Recent studies have to be reported that ghrelin has a close relationship with motilin and the digestive system. In the article we review recent researches of ghrelin on the digestive diseases and its relationship with motilin. |
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| Keywords: | Ghrelin Motilin Gastric emptying MMC H pylori |
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