Current and Future Use of Positron Emission Tomography (PET) in Breast Cancer |
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| Authors: | David A. Mankoff William B. Eubank |
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| Affiliation: | (1) Division of Nuclear Medicine, Department of Radiology, University of Washington and Seattle Cancer Care Alliance, Seattle, WA, USA;(2) Department of Radiology, University of Washington and Puget Sound VA Health Care System, Seattle, WA, USA;(3) Division of Nuclear Medicine, UWMC, Box 356113, Room NN203, 1959 NE Pacific Street, Seattle, WA 91895, USA |
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| Abstract: | Positron emission tomography (PET) is a radiotracer imaging method that is increasingly used in both the clinical care of breast cancer patients and in translational breast cancer research. This review emphasizes current and future clinical applications of PET to breast cancer, and highlights some translational research using PET to elucidate the clinical biology of breast cancer. PET principles are reviewed, followed by a review of current applications of 18F-fluorodeoxyglucose (FDG) to clinical breast cancer care. Finally we review work done with other radiopharmaceuticals beyond FDG designed to image a number of aspects of breast cancer biology, emphasizing those most likely to enter clinical trials in the near future. |
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| Keywords: | PET Breast cancer Imaging Molecular imaging Response evaluation |
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