Issues related to targeted delivery of proteins and peptides |
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| Authors: | Yingjuan Lu Jun Yang Emanuela Sega |
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| Affiliation: | 1Endocyte, Inc, 3000 Kent Avenue, Suite A1-100, 47906 West Lafayette, IN ;2Department of Chemistry, Purdue University, 47907 West Lafayette, IN |
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| Abstract: | While modern genomic and proteomic technology enables rapid screening of novel proteins and peptides as potential drug candidates, design of delivery systems for these biologics remains challenging especially to achieve site-specific pharmacological actions. This article discusses the issues associated with targeted delivery of protein and peptide drugs at physiochemical, physiological, and intracellular levels with a special focus on cancer therapy. |
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| Keywords: | targeted delivery protein therapeutics peptide therapeutics cancer therapy |
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