Peripheral nerve lesion in spongy degeneration of the central nervous system

Summary This report describes a peripheral nerve lesion found in a case of spongy degeneration of the central nervous system. The lesion consisted of abnormal cellular infiltrates in the peri- and endoneurium, axonal changes, and demyelination. Possible relation of the lesion to that of the central nervous system is discussed.Supported by grant NB-02255 from the National Institutes of Health, United States Public Health Service.