| Effect of Compound 962 Capsule on Liver Lipid Peroxidation and Indexes of Thymus Gland and Spleen in Rats |
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| 引用本文： | Jin Chu,Bin Li,Lin Li,Cuifei Ye,Huibo Liu,Shida He. Effect of Compound 962 Capsule on Liver Lipid Peroxidation and Indexes of Thymus Gland and Spleen in Rats[J]. 中国结合医学杂志, 2000, 6(4): 287-289. DOI: 10.1007/BF02947383 |
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| 作者姓名： | Jin Chu Bin Li Lin Li Cuifei Ye Huibo Liu Shida He |
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| 作者单位： | |
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| 基金项目： | ThisstudywasfundedbyScientificCommitteeofBeijing(No.95 1890 6 0 0)andStateMinistryofPersonnel(No.1998) |
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| 摘 要： |
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Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats |
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| Jin Chu,Bin Li,Lin Li,Cuifei Ye,Huibo Liu and Shida He. Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats[J]. Chinese journal of integrative medicine, 2000, 6(4): 287-289. DOI: 10.1007/BF02947383 |
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| Authors: | Jin Chu Bin Li Lin Li Cuifei Ye Huibo Liu Shida He |
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| Affiliation: | (1) Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053 Beijing |
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| Abstract: | Objective: To investigate the effect of compound 962 capsule (abbre. as 962) on liver lipid peroxidation and indexes of thymus and spleen in aged rats.Methods: Rats were divided into young control, aged model, Piracetam, 962 middle dose (0.9 g/kg) and high dose (1.8 g/kg) groups. All test drugs were administrated for 1 month by gastrogavage. The liver lipid peroxidation was determined by thiobarbituric (TBA) method. The thymus index and spleen index were determined by weighing method.Results: 962 (middle and high dose) attenuated liver lipid peroxidation, increased the thymus index of aged rats. There was no effect on spleen index in all drug-treated groups.Conclusion: 962 could decrease liver lipid peroxidation and increase thymus index. It suggested that 962 might be beneficial in retarding aging process. This study was funded by Scientific Committee of Beijing (No. 951890600) and State Ministry of Personnel(No.l998) |
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| Keywords: | traditional Chinese compound aging liver lipid peroxidation thymus index spleen inde |
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