Changes in serum carboxyterminal telopeptide of type I collagen in an experimental model of canine osteomyelitis |
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Authors: | J. P. Philipov M. D. Pascalev B. Y. Aminkov C. D. Grosev |
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Affiliation: | (1) Department of Surgery, Faculty of Veterinary Medicine, 6000 Stara Zagora, Bulgaria |
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Abstract: | Blood biochemical indices of bone turnover were followed up for 1 month in six dogs with experimental osteomyelitis. The bone infection resulted in significant increase in parameters of bone formation (serum bone alkaline phosphatase and serum osteocalcin) and bone resorption [serum carboxyterminal telopeptide of type I collagen (i-ICTP)] as early as the end of the second week after the operation and inoculation. There was strong evidence that serum i-ICTP levels could be useful for the early diagnosis of postoperative complications in veterinary orthopedics, such as posttraumatic osteomyelitis. |
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Keywords: | Carboxyterminal telopeptide Type I collagen Alkaline phosphatase Experimental osteomyelitis Dogs |
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