正常高值血压者24小时动态血压与睡眠障碍的相关性研究

目的研究非杓型正常高值血压与睡眠障碍的相关性。方法对103例某院体检的正常高值血压人员进行24 h动态血压监测和应用匹兹堡睡眠质量指数（PSQI）量表对睡眠质量评定。结果非杓型组46例和杓型组57例正常高值血压,非杓型组24h平均收缩压（SBP）（123.0±7.0）mm Hg（1mm Hg=0.133 kPa）、夜间平均收缩压（119.4±8.1）mm Hg、夜间平均舒张压（67.2±7.5）mm Hg较杓型组（120.0±6.4）mm Hg,（108.3±8.2）mm Hg,（64.5±5.7）mm Hg]高,差异有统计学意义（P〈0.05）。非杓型收缩压夜间下降率（SBPF）分值（6.1±1.2）mm Hg较杓型（10.1±2.1）mm Hg低,差异有统计学意义（P〈0.05）;非杓型组PSQI评分较杓型高,差异有统计学意义（6.8±2.5）分,（5.8±2.4）分,t=-2.062,P〈0.05];PSQI总分与SBPF呈负相关（r=-0.259,P=0.008）,睡眠障碍是影响非杓型的独立危险因素（OR=1.225,P=0.044）。结论睡眠障碍是非杓型高值血压的危险因素。

The study of relationship between 24 hours ambulatory blood pressure and sleep disorders in high- normal blood pressure cases

Objective To investigate the relationship between non dippers high-normal blood pressure and sleep disorder. Methods One hundred and three people with high-normal blood pressure were recruited. Ambulatory blood pressure monitoring and PSQI assessment were simultaneously applied to record blood circadian rhythms and sleep quality. Results There are 46 cases of non dippers high-normal blood pressure and 57 eases of dippers high-normal blood pressure. The 24 h SBP,nSBP,nDBP total scale of non dippers was 123.0±7.0 mmHg, 119.4±8.1 mm Hg and 67.2±7.5 mm Hg, much higher than that of dippers（120.0±6.4） mm Hg, （108.3±8.2）mm Hg,（64.5±5.7） mm Hg respectively （P〈0.05） SBPF total seale of non dippers was mueh lower than that of dippers （P=0.000）.The PSQI total scale of non dippers （n=46） was much higher than that of dippers （n=57）（6.8±2.5,5.8±2.4,t=-2.062,P〈 0.05）;PSQI total score had negative correlation with SBPF （r=-0.259,P=0.008）;sleep disorder was an independent risk faetor influ- encin- non dippers. Conclusions Sleep disorder was a risk factor affecting non dippers of high-noimal blood pressure.