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食管、贲门癌患者手术前后血清铜蓝蛋白含量变化的研究
引用本文:刘继前,杜兴邦,李炳.食管、贲门癌患者手术前后血清铜蓝蛋白含量变化的研究[J].郧阳医学院学报,1994(2).
作者姓名:刘继前  杜兴邦  李炳
作者单位:郧阳医学院教学医院胸外科,十堰市人民医院胸外科,郧阳医学院附院核医学科
摘    要:本文用放射免疫分析法测定了45例食管、贲门癌患者手术前后血清铜蓝蛋白(SCP)含量的变化,并与44例正常人进行对照。结果表明:食管、贲门癌病人手术前后均显著高于对照组(P<0.01);手术后病人SCP呈递减趋势,72h后SCP开始明显下降,与手术前对照(P<0.05)。并观察到术后有转移的患者SCP持续保持高水平。病情稳定者,SCP趋于正常。由此认为:SCP可以作为食管、贲门癌的诊断、判断预后、有否转移和复发的一项重要辅助参考指标。

关 键 词:食管癌,贲门癌,血清铜蓝蛋白,放射免疫分析法

Investigation of Changes of Serum Ceraloplasmin Levels in Cases With Carcioma of Esophagus or Cardiac Cancer Before and After the Operation
Liu Jiqian,et al.Investigation of Changes of Serum Ceraloplasmin Levels in Cases With Carcioma of Esophagus or Cardiac Cancer Before and After the Operation[J].Journal of Yunyang Medical College,1994(2).
Authors:Liu Jiqian  
Abstract:The changes of levels of serum ceruloplasin(SCP)were measured aamong 45 cases with carcinoma of esophagus or cardiac cancer before and after the operations,using radio-immunity analysis and the results were contrasted with those of the normal group which consisted of 44 cases.The results showed that the patients' levels of SCP before and after the operation were markedly higher than those of the control group(P<0.01)and that in contrast with those before the operation (P<0.01)a tendcy to decrease stably,which was quite obvions in 72 hours after the operation.It was observed that with cases who had metastases after the operation,their SCP kept a high level,where as with those cases whose disease was under control,the SCP almost returned to normal levels.Therefore it is considered that levels of SCP provide an important auxiliary reference index for the diagnosis,prognosis of both cancers and the judgement of metastasis or recurrence.
Keywords:carcinoma of esophagus  cardiac cancer serum  ceruloplasmin  radio-immunity analysis
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