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紫杉醇联合顺铂治疗复发性宫颈癌的临床观察
引用本文:Yingqiu Song,Guiling Li,Fang Zhu,Fangzheng Zhou,Sheng Zhang,Jing Wang,Zhongyuan Ying.紫杉醇联合顺铂治疗复发性宫颈癌的临床观察[J].中德临床肿瘤学杂志,2007,6(3):P282-P284.
作者姓名:Yingqiu Song  Guiling Li  Fang Zhu  Fangzheng Zhou  Sheng Zhang  Jing Wang  Zhongyuan Ying
作者单位:Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430023, China
摘    要:Objective: To observe the efficacy and toxicities of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer. Methods: Twenty-three patients with a diagnosis of recurrent cervical cancer were eligible. Three-weekly chemotherapy regimen consisted of paclitaxel 135-150 mg/m^2 infusion for 3 h on day 1, cisplatin 25 mg/m^2 infusion on day 1 to 3. All patients received at least two cycles treatment. Results: The response rates was 47.8%, including CR 2 cases (8.7%), PR 9 cases (39.1%). The major toxicity included neutropenia, nausea vomiting, arthralgia, myalgia and alopecia. Conclusion: Paclitaxel combined with cisplatin is an effective therapy with acceptable adverse reactions for recurrent cervical cancer.

关 键 词:化学疗法  子宫颈癌  反复发作  治疗方法
收稿时间:26 January 2007
修稿时间:2007-02-262007-03-07

Clinical study of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer
Yingqiu?Song,Guiling?Li,Fang?Zhu,Fangzheng?Zhou,Sheng?Zhang,Jing?Wang,Zhongyuan?Ying.Clinical study of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer[J].The Chinese-German Journal of Clinical Oncology,2007,6(3):P282-P284.
Authors:Yingqiu Song  Guiling Li  Fang Zhu  Fangzheng Zhou  Sheng Zhang  Jing Wang  Zhongyuan Ying
Institution:(1) Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430023, China
Abstract:Objective:To observe the efficacy and toxicities of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer.Methods:Twenty-three patients with a diagnosis of recurrent cervical cancer were eligible.Three-weekly chemotherapy reqimen consisted of paclitaxel 135-150 mg/m2 infusion for 3 h on day 1.cisplatin 25 mg/m2 infusion on day 1 to 3.All patients received at least two cycles treatment.Results:The response rates was 47.8%,including CR 2 cases(8.7%),PR9 cases(39.1%).The major toxicity included neutropenia,nausea vomiting,arthralgia,myalgia and alopecia.Conclusion:Paclitaxel combined with cisplatin is an effective therapy with acceptable adverse reactions for recurrent cervical cancer.
Keywords:paclitaxel  cisplatin  chemotherapy  recurrent cervical cancer
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