Imaging findings of recurrent acute lymphoblastic leukemia in children and young adults,with emphasis on MRI

Acute lymphoblastic leukemia (ALL) is the most common of all childhood malignancies. Current remission rates approach 80%. Recurrent disease can present in a wide variety of ways. MR imaging plays a crucial role in the detection of disease relapse. Because other disorders can mimic recurrence of leukemia, it is important for the radiologist to judge recurrence from non-recurrence accurately in order to avoid unnecessary testing and emotional stress on the patient and family.This study was supported in part by grants P30 CA-21765 and P01 CA20180 from the National Cancer Institute and by the American Lebanese Syrian Associated Charities (ALSAC)