快冻和慢冻法对胚胎复苏结局的比较

目的:比较辅助生殖技术中快冻(玻璃化法)和慢冻(程序化法)两种冷冻方法对卵裂期胚胎的冻融效果.方法:将复苏后全部卵裂球存活的胚胎定义完整存活胚胎,同一病人由于有多余冻融胚胎而行2次及以上移植周期的称为重复周期.对577个快冻周期和276个慢冻周期的相关资料进行回顾性统计学分析,比较两组冻融胚胎的存活率、完整存活率、重复...

Comparion of the Outcomes Between Vitrification and Slow-Freezing Methods for Cryopreservation of Embryos in Cleavage Stage

Objective: To compare the outcomes of vitrification and slow-freezing methods for cryopreservation of cleavage stage embryos in assisted reproductive technology.Methods: A retrospective statistical analysis was performed in our center on 577 vitrification cycles and 276 slow-freezing cycles.The embryo survival and intact survical rate after embryo recovery,embryo implantation rate and clinical pregnancy rate and other indicators were compared.Results: In rapid freezing group,the numbers of embryos thawed each cycle were less than in the slow-freezing group,but the numbers of survival embryos were more,and the period recurrence rate was higher.Vitrified embryos was superior to the procedural slowly-frozen embryos in embryo survival rate,intact embryo survival rate,embryo implantation rate,clinical pregnant rate,and transfer cancel rate(all P<0.05).Conclusion: Vitrification is better to preserve the potential development of frozed embryo after recovery,and is an ideal method for cryopreservation of the cleavage embryos.