| 银翘散主要药物提取物体外抑制流感病毒作用的比较研究 |
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| 引用本文： | 潘曌曌,王雪峰,南春红,闫丽娟,岳志军.银翘散主要药物提取物体外抑制流感病毒作用的比较研究[J].中医儿科杂志,2011,7(1):9-12. |
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| 作者姓名： | 潘曌曌 王雪峰 南春红 闫丽娟 岳志军 |
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| 作者单位： | 辽宁中医药大学附属医院,辽宁,沈阳,110032 |
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| 基金项目： | 国家教育部博士点基金课题 |
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| 摘 要： | 目的:观察并比较银翘散主要药物金银花、连翘、牛蒡子及其配伍提取物体外抗甲型流感病毒FM1株作用.方法:采用血凝试验对中药不同浓度、不同时间点进行体外抗甲型流感病毒的效价测定.结果:金银花、连翘、牛蒡子及其配伍提取物可直接抑制甲型流感病毒FM1株的活性,作用时间从1 h可持续到24 h;各时间点各中药提取物在最大不凝血浓度即金银花25 mg/mL、连翘50 mg/mL、牛蒡子100 mg/mL、配伍组50 mg/mL时均能完全抑制病毒的增殖,其对病毒的抑制作用随着药物浓度的降低而逐渐减弱.结论:金银花、连翘、牛蒡子及其配伍提取物可有效抑制甲型流感病毒FM1株体外增殖.
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| 关 键 词： | 甲型流感病毒 金银花 连翘 牛蒡子 配伍 提取物 |
Comparative studies on depressant effect which main extracts from Yinqiao San inhibiting influenza A virus FM1 strain in vitro |
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| Pan Zhaozhao,Wang Xuefeng,Nan Chunhong,Yan Lijuan,Yue Zhijun.Comparative studies on depressant effect which main extracts from Yinqiao San inhibiting influenza A virus FM1 strain in vitro[J].Journal of Pediatrics of Traditional Chinese Medicine,2011,7(1):9-12. |
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| Authors: | Pan Zhaozhao Wang Xuefeng Nan Chunhong Yan Lijuan Yue Zhijun |
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| Institution: | Pan Zhaozhao,Wang Xuefeng,Nan Chunhong,Yan Lijuan,Yue Zhijun(Affiliated Hospital of Liaoning University of TCM,Shenyang,Liaoning,110032,China) |
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| Abstract: | Objective:To observe and compare the effect that extracts from Lonicerae japonica Thunb.,Forsythia suspensa(Thunb.) Vahl,Arctium Lappa L.and their compatibility inhibiting influenza A virus FM1 strain in vitro.Methods: Used the method of hemagglutination(HI)test,determined the hemagglutination inhibition titer that extracts from herbs of different concentration inhibiting IV in vitro at different time spot.Results:Extracts from Lonicerae japonica Thunb.,Forsythia suspensa(Thunb.) Vahl, Arctium Lappa L.and t... |
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| Keywords: | influenza A virus Lonicerae japonica Thunb Forsythia suspensa(Thunb ) Vahl Arctium Lappa L compatibility extracts |
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