Activity of cathelicidin peptides against Chlamydia spp |
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| Authors: | Donati Manuela Di Leo Korinne Benincasa Monica Cavrini Francesca Accardo Silvia Moroni Alessandra Gennaro Renato Cevenini Roberto |
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| Affiliation: | Sezione di Microbiologia, DMCSS, Policlinico S.Orsola, Università di Bologna, Via Massarenti 9, 40138 Bologna, Italy. |
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| Abstract: | The in vitro activity of six cathelicidin peptides against 25 strains of Chlamydia was investigated. SMAP-29 proved to be the most active peptide, reducing the inclusion numbers of all 10 strains of Chlamydia trachomatis tested by > or =50% at 10 microg/ml. This peptide was also active against C. pneumoniae and C. felis. |
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