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急性胰腺炎患者凝血、纤溶功能的变化检测及意义
引用本文:何毅. 急性胰腺炎患者凝血、纤溶功能的变化检测及意义[J]. 川北医学院学报, 2005, 20(1): 91-92
作者姓名:何毅
作者单位:达州职业技术学院,四川,达州,635000
摘    要:目的探讨33例急性胰腺炎患者凝血及纤溶系统的变化及临床意义。方法用全自动血凝分析仪,检测急性胰腺炎组和正常对照组的凝血酶原时间(PT)、部分活化凝血酶原时间(APPT)和纤维蛋白原浓度(FIB)。ELISA法检测D-二聚体(D-dimmer)。结果在各项指标中,轻型急性胰腺炎组与对照组比较差异无显著性(P>0 05);重症急性胰腺炎组和对照组比较差异有显著性(P<0 01)结论重症急性胰腺炎病人PT、APTT和FIB、D-dimmer值明显异常,且提示预后不佳。早期监测急性胰腺炎患者凝血、纤溶功能对病情的转归判断与预后有重要意义。

关 键 词:急性胰腺炎  凝血  纤溶
文章编号:1005-3697(2005)01-0091-02
修稿时间:2005-01-30

Detection and importance of changes in the coagulation and fibrinolysis in patients with acute pancreatitis
HE Yi. Detection and importance of changes in the coagulation and fibrinolysis in patients with acute pancreatitis[J]. Journal of North Sichuan Medical College, 2005, 20(1): 91-92
Authors:HE Yi
Affiliation:Dazhou Vocational College of Technology
Abstract:Objective To investigate the changes and clinical significance of the coagulation and fibrinolysis in 33 patients with acnte pancreatitis;Methods prothrombin time(PT), activated partial prothrombin time(APPT) and fibrinogen (FIB) were measared with an automatic analyser, and the D-dimmer was detected with the ELISA method.Results There were no significant differences in the parameters measared between the mild acute pancreatitis and control groupa (P>0 05),while sigificant differences were detected in severe acute patients (P<0 01).Conclusion There were considerable changes in the PT,APPT, FIB and D-dimmer in severe acute pancereatitis patiencts, and thses changes also suggested poor prognosis.
Keywords:pancreatitis  coagulation  fibinolysis
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