Synthesis of imidazole derivatives containing biologically active units |
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| Authors: | Abdel Ghani Ali Elagamey Abdel Fattah Ali Harb Mohamed Nabil Khodeir Salah Zaki Ahmed Sowellim |
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| Institution: | 1. Faculty of Science, Damietta, Mansoura University, Damietta
2. Faculty of Science, Qena, Assiut University, Qena, Egypt
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| Abstract: | Reaction of oxazolin-5-ones1 withp-amino-diphenylamine was resulted in the formation of the corresponding imidazolin-5-ones2 which on treatment with sulphur afforded phenothiazines3. Acridine derivatives5 were obtained from acetylaminodiphenylamines derivatives6 on heating with ZnCl2 at 200°C.3 reacted with chloroacetyl chloride to give7 which reacted in turn with different amines to give8. Antibacterial activity of the obtained products was studied. |
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