| 职业性急性二氯五氟丙烷中毒临床分析 |
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| 引用本文： | 郑倩玲,陈嘉斌,梁伟辉,梁顺华,余意玉. 职业性急性二氯五氟丙烷中毒临床分析[J]. 新医学, 2011, 42(7): 436-439. DOI: 10.3969/g.issn.0253-9802.2011.07.005 |
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| 作者姓名： | 郑倩玲 陈嘉斌 梁伟辉 梁顺华 余意玉 |
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| 作者单位： | 广东省职业病防治院,510300 |
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| 摘 要： | 目的：探讨职业性急性二氯五氟丙烷（HCFC-225）中毒的临床特点及治疗方法。方法：回顾性分析2010年12月一起职业中毒事故中6例急性HCFC-225中毒患者的临床资料。结果：本组6例患者均有明确的急性泄露事故导致吸入HCFC-225的职业接触史，急性起病，均被诊断为职业性急性HCFC-225中毒。多数患者出现头晕、眼花、头痛、乏力、步态蹒跚、胸闷、恶心等，部分患者出现呕吐、咳嗽、咽痛、鼻塞、流涕等，严重者可出现意识障碍。体征方面，所有患者均出现急性病容和四肢肌力下降，5例出现呼吸音增粗，个别呼吸急促，严重者出现烦躁不安、嗜睡、昏睡、昏迷。中枢神经系统症状改变与HCFC-225接触时间呈剂量．效应关系。患者中毒第2日外周血白细胞计数均升高，1例患者胸部X线片示急性支气管炎改变，1例昏迷患者出现脑电图低电压改变，另1例出现动脉血氧分压偏低。糖皮质激素和脱水治疗有效。结论：职业性急性HCFC-225中毒的临床表现以中枢神经系统和呼吸系统的损害为主，及时的脱水治疗和早期、足量、短程糖皮质激素是治疗的关键。
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| 关 键 词： | 二氯五氟丙烷 中毒 中枢神经系统 呼吸系统 |
Clinical analysis of occupational acute poisoning of HCFC-255 |
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| ZHENG Qian-ling,CHEN Jia-bin,LIANG Wei-hui,LIANG Shun-hua,YU Yi-yu. Clinical analysis of occupational acute poisoning of HCFC-255[J]. New Chinese Medicine, 2011, 42(7): 436-439. DOI: 10.3969/g.issn.0253-9802.2011.07.005 |
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| Authors: | ZHENG Qian-ling CHEN Jia-bin LIANG Wei-hui LIANG Shun-hua YU Yi-yu |
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| Affiliation: | ZHENG Qian-ling,CHEN Jia-bin,LIANG Wei-hui,LIANG Shun-hua,YU Yi-yu.Guangdong Prevention and Treatment Centre for Occupational Disease,Guangzhou 510300,China |
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| Abstract: | Objective: To study the clinical features and treatments of occupational acute poisoning of HCFC-225.Methods: Clinical data of 6 patients wtih acute poisoning of HCFC-225 from an industrial accident in December 2010 were analyzed retrospectively.Results: The 6 patients were diagnosed of occupational acute poisoning of HCFC-225 according to acute onset and occupational exposure of HCFC-255 inhalation in an acute leakage accident.Symptoms,such as dizziness,giddiness,headache,fatigue,waddling gait,nausea and c... |
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| Keywords: | HCFC-225 Poisoning Central nervous system Respiratory system |
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