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Quantitative histological measurements of bone turnover in primary hyperparathyroidism |
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| Authors: | Dr. C. D. Wilde Z. F. Jaworski A. R. Villanueva H. M. Frost |
| Affiliation: | 1. Department of Surgery, Division of Traumatology, Hannover Medical School, Hannover, Michigan 3. Department of Medicine, University of Ottawa and Ottawa General Hospital, Ontario, Michigan 4. Orthopaedic Research Laboratory, Henry Ford Hospital, Detroit, Michigan 5. Department of Orthopaedic Surgery, Henry Ford Hospital, Detroit, Michigan |
| Abstract: | Undecalcified tetracycline labeled rib biopsies of 7 patients with clinical primary hyperparathyroidism and proven adenoma of the parathyroid glands were examined histologically to study the bone remodeling effects of parathyroid hormone. Unexpectedly wide variations of the static and dynamic bone remodeling data in this group of clinically similar patients was found. Explanations for this conduct still remain highly speculative. |
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