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153例丹参不良反应文献分析
引用本文:金剑,金芝贵,肖忠革,吴飞华.153例丹参不良反应文献分析[J].中国药物警戒,2010,7(6):370-372.
作者姓名:金剑  金芝贵  肖忠革  吴飞华
作者单位:上海交通大学医学院附属第九人民医院药剂科,上海,200011
摘    要:目的分析丹参不良反应的一般规律和特点,为临床预防或避免该类药品不良反应(ADR)的发生提供参考。方法通过检索文献资料,查阅l993~2009年国内公开发表的中文医药期刊,对有关丹参的不良反应进行分类统计分析。结果丹参所致的ADR报道共153例,女性较多;不良反应临床表现以全身损害和变态反应为主,占总例数的58.8%。结论临床医护人员应当重视丹参的不良反应,了解发生规律,采取合理有效的处理方法,从而使临床用药更为安全合理。

关 键 词:丹参  药品不良反应

Analysis of 153 Cases of Adverse Drug Reaction Caused by Salvia miltiorrhiza
JIN Jian,JIN Zhi-gui,XIAO Zhong-ge,WU Fei-hua.Analysis of 153 Cases of Adverse Drug Reaction Caused by Salvia miltiorrhiza[J].Chinese JOurnal of Pharmacovigilance,2010,7(6):370-372.
Authors:JIN Jian  JIN Zhi-gui  XIAO Zhong-ge  WU Fei-hua
Institution:(Deparment of Pharmacy,Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China)
Abstract:Objective To analyze the general pattern and features of adverse drug reaction(ADR) induced by Salvia miltiorrhiza for reference of rational drug use in the clinic. Methods The Salvia miltiorrhiza induced ADR cases reported in China from 1993 to 2009 were collected and analyzed. Results There were 153 cases,females over males in ADR cases. Total body damage and allergic reaction was the major ADR type(58.8%). Conclusion Clinicians should attach great importance to the ADR caused by Salvia miltiorrhiza and understand regular pattern of occurrence and take reasonable and effective method to ensure medication safety.
Keywords:Salvia miltiorrhiza  adverse drug reaction(ADR)
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