THE SKIN CHANGES IN SCLERODERMA (SYSTEMIC SCLEROSIS)

Scleroderma (systemic sclerosis) may be subdivided into an acrosclerotic form (Types 1 and 2) and a diffuse form (Type 3) on the extent of the skin involvement. The acrosclerotic form has generally a relatively good prognosis and the diffuse form a poor prognosis. Although there is a general tendency for the skin sclerosis to progress, the change may be slow and may halt. Other skin manifestations include pigmentation, telangiectases, calcinosis, hyperkeratoses and various forms of ulceration. Recent studies on electron microscopy and biochemical findings in scleroderma skin are described. They indicate the presence of young collagen.