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hs-CRP、FIB检测对脑梗死患者的意义
引用本文:张阿宁.hs-CRP、FIB检测对脑梗死患者的意义[J].检验医学与临床,2016(17):2453-2454.
作者姓名:张阿宁
作者单位:延安大学附属医院神经内科,陕西延安,716000
摘    要:目的分析和研究超敏C反应蛋白(hs-CRP)、纤维蛋白原(FIB)对脑梗死患者的意义。方法选取2014年10月至2015年11月于该院进行治疗的脑梗死患者100例作为患者组。另外,随机选取2015年2月至2015年11月于该院进行体检的健康人100例作为对照组。检测和比较两组人群的hs-CRP、FIB水平,统计分析其与神经功能评分的相关性。结果患者组FIB、hs-CRP水平均高于对照组,差异有统计学意义(P0.05)。患者hs-CRP、FIB水平均与NIHSS评分呈正相关(r分别为0.291、0.891,P0.05)。结论 hs-CRP、FIB水平的升高与脑梗死的发病关系密切,及时检测这两项指标的水平变化有助于脑梗死的早发现、早治疗。

关 键 词:超敏C反应蛋白  纤维蛋白原  脑梗死

The significance of FIB and hs-CRP detection in patients with cerebral infarction
Abstract:Objective To analyze and study the significance of high‐sensitive C reactive protein(hs‐CRP) and fibrinogen (FIB) determination in patients with cerebral infarction .Methods 100 patients with cerebral infarction treated in the hospital from Octo‐ber 2014 to November 2015 were enrolled in the study as the patient group .In addition to that ,100 healthy people who had under‐went healthy examination in the hospital were randomly enrolled in the study from February 2015 to November 2015 .The serum concentrations of hs‐CRP and FIB of the two groups were detect and compared ,and the correlation between hs‐CRP ,FIB concentra‐tions and neurological function scores were also analyzed .Results The concentrations of FIB and hs‐CRP in the patients group was higher than that in the control group ,the difference was statistically significant(P<0 .05) .Patients′hs‐CRP ,FIB levels were posi‐tively correlated with the NIHSS scores(r were 0 .291 ,0 .891 respectively ,P<0 .05) .Conclusion The concentrations of hs‐CRP and FIB increasing were closely related to the incidence of cerebral infarction .Detecting the concentration changes of the two indica‐tors in time is helpful for the early detection and early treatment of cerebral infarction .
Keywords:high-sensitivity C-reactive protein  fibrinogen  cerebral infarction
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