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有机磷农药中毒合并呼吸衰竭患者洗胃治疗方法研究
引用本文:朱敏,王斌.有机磷农药中毒合并呼吸衰竭患者洗胃治疗方法研究[J].检验医学与临床,2016(16).
作者姓名:朱敏  王斌
作者单位:江苏省徐州市肿瘤医院重症监护科 221005
基金项目:江苏省徐州市科技局推动科技创新后补助备案项目(KC14SH013)。
摘    要:目的探讨更为有效的有机磷农药中毒合并呼吸衰竭患者的洗胃治疗方法。方法将该院急诊科收治的有机磷农药中毒合并呼吸衰竭患者60例随机分为对照组和观察组,每组30例。对照组给予常规方法洗胃治疗,观察组给予改进的洗胃治疗方法。比较两组患者中需进行反复胃管插管的患者比例,到达阿托品化的时间,并发症发生情况,治愈率及住院时间。结果观察组反复插管患者比例、达阿托品化的时间、发生反跳的比例、洗胃液呈红色的比例及住院时间低于对照组,且治愈率高于对照组(P0.05);发生大泡性皮疹的比例两组间比较差异无统计学意义(P0.05)。结论采用呼吸道插管技术及辅助呼吸机治疗有机磷农药中毒合并呼吸衰竭的患者,不仅可有效避免反复插管,缩短达到阿托品化的时间,也有助于避免并发症的发生,提高患者生存率和缩短住院时间,值得临床推广应用。

关 键 词:有机磷农药中毒  呼吸衰竭  洗胃

Research of gastric lavage treatment in organophosphorus pesticide poisoning patients with respiratory failure
Abstract:Objective To investigate the curative effects of improved gastric lavage treatment in organophosphorus pesticide poi-soning(OPP) patients with respiratory failure .Methods Sixty OPP patients with respiratory failure ,treated in the Emergency De-partment of this hospital ,were randomly divided into control group and observation group ,with 30 cases in each group .Patients in control group were given conventional gastric lavage treatment ,and those in observation group were given modified gastric lavage treatment .The proportion of repeated intubation ,time to reach atropinization ,incidence of complications ,cure rate and hospitaliza-tion time were compared between the two groups .Results The proportion of repeated intubation ,time to reach atropinization ,inci-dence of rebound ,incidence of red drainage of gastric juice and hospitalization time of observation group were lower than control group ,while cure rate were higher(P< 0 .05) .Difference of incidence of bullous rash were not significant between the two groups (P> 0 .05) .Conclusion Airway intubation and assisted ventilation treatment could not only effectively reduce the proportion of re-peated intubation ,shorten the time to reach atropinization ,avoid the occurrence of complications ,improve survival rate of patients , but also shorten hospitalization time ,which might be worthy of promotion .
Keywords:organophosphorus pesticide poisoning  respiratory failure  gastric lavage
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