瑞舒伐他汀钙对脑梗死患者动脉粥样硬化及脑血流动力学的改善作用研究

目的探讨瑞舒伐他汀钙对脑梗死患者动脉粥样硬化及脑血流动力学的改善作用。方法将2014年1月至2015年6月于该院就诊的脑梗死确诊患者100例分为对照组和试验组,每组各50例。所有患者均给予常规治疗,试验组患者在常规治疗基础上口服瑞舒伐他汀钙。比较不同治疗方案对颈内动脉粥样硬化斑块及脑血流动力学的影响。结果治疗后,试验组不稳定动脉粥样硬化斑块检出率小于对照组(P0.05));试验组和对照组患者血流动力学均有所改善,试验组改善更显著,血流动力学指标组间比较差异有统计学意义(P0.05)。结论瑞舒伐他汀钙可稳定和逆转动脉斑块,减少动脉粥样硬化发病率,改善脑梗死患者脑血流动力学指标,降低不良事件发病率,值得推广应用。

Improving effects of rosuvastatin calcium on atherosclerosis and cerebral blood flow dynamics in patients with cerebral infarction

Objective To analyze the improving effects of rosuvastatin calcium on atherosclerosis and cerebral blood flow dy-namics in patients with cerebral infarction(CI) .Methods A total of 100 cases of CI patients ,treated in this hospital during Jan . 2014 and Jun .2015 ,were divided into experimental group and control group ,with 50 cases in each group .All patients were given conventional treatment ,while the experimental group was given oral treatment of rosuvastatin calcium on the basis of conventional treatment .Effects of the different treatments on internal carotid atherosclerosis plaque and cerebral blood flow dynamics were com-pared .Results After treatment ,unstable atherosclerotic plaque detection rate of experimental group was significantly lower than control group(P< 0 .05) .Hemodynamics of experimental group and control group were both improved ,but the experimental group was with more significant improvement ,and the differences were statistically significant(P< 0 .05) .Conclusion Rosuvastatin calci-um treatment could stable and reverse artery plaque ,reduce the incidence of atherosclerosis ,improve cerebral hemodynamic index , reduce the incidence of adverse events and be with reliable curative effects ,which might be worth of clinical promotion .