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胃粘膜管样异型增生的免疫组化研究
引用本文:赵肖宪,赵刚. 胃粘膜管样异型增生的免疫组化研究[J]. 中国肿瘤临床与康复, 1998, 5(2): 11-12
作者姓名:赵肖宪  赵刚
作者单位:北京职工医学院基础部!100036(赵肖宪),北京医科大学(赵刚,刘树卿)
摘    要:胃癌的癌前病变研究是目前胃粘膜病变研究中的热点。本文对胃炎、胃粘膜管样异型增生及胃癌进行了Ki-67及CEA免疫组织化学研究,结果发现Ki-67及CEA的阳性表达率在胃炎、管样异型增生及胃癌中呈明显递增趋势。从而提示管样异型增生可能是胃癌发病过程中重要的过渡阶段,是其癌前病变中的一种类型。应引起病理和临床上的重视。

关 键 词:管样异型增生  癌前病变  胃癌  Ki-67  CEA

Immunohistochemical study of tuboid dysplasia of gastric mucosal epithelium
Zhao Xiaoxian, Zhao Gang, Liu Shuqing. Immunohistochemical study of tuboid dysplasia of gastric mucosal epithelium[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 1998, 5(2): 11-12
Authors:Zhao Xiaoxian   Zhao Gang   Liu Shuqing
Abstract:The exploration of the precancerous lesion of gastric cancinoma is a hotspot in the re-search of gastric disease. In this article,the Ki-67 and CEA im munch istochemical study were operated inconnection with gastritis, tuboid dysplasia of gastric mucosal epithelium (TD) and gastric cancinoma.The results showed that the positivity of the immunohistochemical staining had an obvious upward ten-dency in these diseases, which indicates TD may be an important step in the process of gastric cancinomaand a kind of precancerous lesion of gastric carcinoma. Therefore, TD should be well recognized by thepathological and clinical field.[
Keywords:tuboid dyspladia   precancerous lesion   gastric carcinoma   Ki-67   CEA
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