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搅拌转速对川贝超细粉体浸提的影响
引用本文:林周,陈长洲,孙冬梅,彭俊锋.搅拌转速对川贝超细粉体浸提的影响[J].中药新药与临床药理,2005,16(4):282-284.
作者姓名:林周  陈长洲  孙冬梅  彭俊锋
作者单位:1. 中药提取分离过程现代化国家工程研究中心/广州汉方现代中药研究开发有限公司,广州,510240
2. 广东省中医研究所,广州,510095
摘    要:目的研究搅拌转速对川贝超细粉体浸提的影响.方法在不同搅拌转速下测定400目川贝超细粉的浸出率,并与100目川贝细粉进行比较.同时对浸提过程应用双曲线函数及威布尔函数建立的数学模型进行比较.结果搅拌转速高于70 r/min时,川贝超细粉120 min的累积浸出率高于川贝细粉(P<0.05),搅拌转速低于70 r/min时,两者无显著差异(P>0.05).应用双曲线函数拟合浸出过程优于采用威布尔函数.结论搅拌转速对川贝超细粉的浸出率有较大影响,提示在川贝的超细粉碎研究和生产中应注意到扩散作用对浸出作用的影响.

关 键 词:川贝  超细粉体  浸出率  数学模型
文章编号:1003-9783(2005)04-0282-03
修稿时间:2005年3月17日

Influence of Mill Speed on Extract of Ultra - fine Powder of Bulbus Fritillariae Cirrhosae
Lin Zhou,CHEN Changzhou,Sun Dongmei,PENG Junfeng.Influence of Mill Speed on Extract of Ultra - fine Powder of Bulbus Fritillariae Cirrhosae[J].Traditional Chinese Drug Research & Clinical Pharmacology,2005,16(4):282-284.
Authors:Lin Zhou  CHEN Changzhou  Sun Dongmei  PENG Junfeng
Abstract:Objective To study the influence of mill speed on extract of ultra- fine powder of Bulbus Fritillariae Cirrhosae. Methods The extraction rate of ultra- fine powder of Bulbus Fritillariae Cirrhosae, which passed a 400- mesh screen, was detected and compared with that passed a 100- mesh screen under different mill speeds. At the same time, mathematical models for extraction established with applied hyperbolic function and Weibuer function were compared. Result The extraction rate of the ultra- fine powder was higher than that of the fine powder when the mill speed was over 70 r/min (P < 0.05), while the difference was not significant when the mill speed was lower than 70 r/min(P > 0.05). Applied hyperbolic function was superior to Weibuer function for the simulation of extraction. Conclusion The mill speed has an influence on the extraction of to ultra- fine powder of Bulbus Fritillariae Cirrhosae, indicating that the effect of divergent function on the extraction should be considered.
Keywords:Bulbus Fritillariae Cirrhosae  Ultra- fine powder  Extraction rate  Mathematical model  
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