Diagnostic and therapeutic use of monoclonal antibodies to human tumor antigens

Monoclonal antibodies have been obtained to various differentiation antigens that are more strongly expressed on tumor cells than on normal cells from the adult host, some of these antigens are relatively specific for tumors of a given type, e.g. melanoma. Monoclonal anti-tumor antibodies offer strong promise for clinical use, initially for tumor diagnosis and, ultimately, also for therapy.