阿卡波糖与格列美脲联合治疗新诊断2型糖尿病患者的疗效观察 |
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引用本文: | 李国华,赵德水,成威.阿卡波糖与格列美脲联合治疗新诊断2型糖尿病患者的疗效观察[J].中国当代医药,2009,16(16):74-75. |
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作者姓名: | 李国华 赵德水 成威 |
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作者单位: | 湖南省湘潭市中心医院内分泌科,湖南湘潭,411100 |
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摘 要: | 目的:观察阿卡波糖(拜唐苹)和格列美脲联合治疗新诊断2型糖尿病的疗效及安全性。方法:收集2008年6月~2009年2月本院专科门诊及住院患者中新诊断2型糖尿病共65例,予阿卡波糖和格列美脲联合治疗,治疗前及治疗12周后测定体重指数(BMI)、空腹血糖(FBG)、餐后2h血糖(PBG)、糖化血红蛋白(HbA1c)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL-C)、肝肾功能,同时观察药物副作用。结果:治疗12周后血糖及血脂指标较治疗前有明显改善,低血糖反应发生率63%,无严重低血糖事件发生。结论:阿卡波糖与格列美脲联合治疗新诊断2型糖尿病控制血糖血脂效果好,副作用轻微。
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关 键 词: | 阿卡波糖 格列美脲 新诊断2型糖尿病 |
Clinical observation on the effect of Acarbose combined with Glimepiride on newly diagnosed type 2 diabetes mellitus |
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Authors: | LI Guohua ZHAO Deshui CHENG Wei |
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Institution: | (Division of endocrinology of Xiangtan Centeral Hospital,Xiangtan 411100,China) |
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Abstract: | Objective:To observe the effect and safety of Acarbose (Glucobay) combined with Glimepiride on patients with type 2 diabetes mellitus (T2DM).Methods:Sixty-five patients with T2DM were treated with Acarbose and Glimepiride.The levels of BMI,FBS,PBG,HbA1c,TC,TG and LDL-C were determined before treatment and 12 weeks after treatment.At the same time side effects were observed.Results:Twelve weeks after treatment the levels of blood sugar and blood lipid were reduced significantly.Side effect including gastrointestinal tract reaction and hypoglycemia was rare.Conclusion:Acarbose in combination with Glimepiride is effective for treatment of patients with T2DM. |
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Keywords: | Acarbose Glimepiride Type 2 Diabetes Mellitus |
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