| 亚硒酸钠对艾氏腹水癌(实体型)生长的抑制作用 |
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| 引用本文： | 倪璇,王继尧. 亚硒酸钠对艾氏腹水癌(实体型)生长的抑制作用[J]. 华中科技大学学报(医学版), 1988, 0(5) |
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| 作者姓名： | 倪璇 王继尧 |
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| 作者单位： | 同济医科大学公共卫生学院营养与食品卫生学教研室(倪璇)，同济医科大学公共卫生学院营养与食品卫生学教研室(王继尧) |
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| 摘 要： | 本文用“肿瘤抑制率”为指标,观察亚硒酸钠对艾氏腹水癌(实体型)生长的抑制作用。3个实验组小鼠腹腔注射亚硒酸钠,剂量分别为1/7LD_(50)(3.50mg/kg体重)、1/10LD_(50)(2.45mg/kg体重)和1/30LD_(50)(0.82mg/kg体重)每日给药1次,共7天。结果以1/10LD_(50)组的“肿瘤抑制率”为最高,经体重校正瘤重后,“肿瘤抑制率”仍高达35.59％。
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| 关 键 词： | 亚硒酸钠 艾氏腹水癌 肿瘤抑制率 |
Antitumor Effect of Sodium Selenite on Ehrlich Ascites Tumor (Solid Form) |
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| Ni Xuan,Wang Jiyao. Antitumor Effect of Sodium Selenite on Ehrlich Ascites Tumor (Solid Form)[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1988, 0(5) |
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| Authors: | Ni Xuan Wang Jiyao |
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| Affiliation: | Ni Xuan,Wang JiyaoDepartment of Nutrition and Food Hygiene,School of Public Health,Tongji Medical University,Wuhan |
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| Abstract: | Inhibition ratio was used as an index to observe the antitumor effect of sodium selcnite on Ehrlich ascites tumor (solid form). Sodium selenite was given I.P. to all 3 experimental groups of mice; the dose was 1/7 LD50(3.50mg/kg body wt.), 1/10 LD50 (2.45mg/kg body wt) and 1/30 LD50 (0.82mg/kg body wt) respectively, given once a day for 7 days. The results showed that 1/10 LD50 group had the highest inhibition ratio, amounting to 35.59% even after checking the tumor weight by body weight. |
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| Keywords: | sodium selente Ehrlich ascites tumor inhibition ratio |
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