| 正交试验法优选虫草安肺片提取工艺 |
| |
| 引用本文： | 吴志恒,费超,王成芳,杜树山. 正交试验法优选虫草安肺片提取工艺[J]. 中国实验方剂学杂志, 2012, 18(8): 4-6 |
| |
| 作者姓名： | 吴志恒 费超 王成芳 杜树山 |
| |
| 作者单位： | 1. 武警医学院附属医院药剂科,天津,300162
2. 北京师范大学中药资源保护与利用北京市重点实验室,北京,100875 |
| |
| 基金项目： | 国家科技支撑计划课题(2007BAI48B10);重大新药创制科技专项(2009ZX09103-325) |
| |
| 摘 要： | 目的:优选虫草安肺片的提取工艺.方法:以盐酸麻黄碱提取量为评价指标,HPLC测定含量,选择加水量、提取时间、提取次数为考察因素,采用L9(34)正交试验优选虫草安肺片的提取工艺.结果:最佳提取工艺为分别加10,8,8倍量水煎煮2,1,1h.结论:优选出的提取工艺简单、可行,适应大生产需要,可作为该制剂合理开发的依据.
|
| 关 键 词： | 虫草安肺片 提取工艺 正交试验 盐酸麻黄碱 高效液相色谱法 |
| 收稿时间： | 2011-12-04 |
Optimization of Extraction Process of Chongcao Anfei Tablet by Orthogonal Design |
| |
| WU Zhi-heng,FEI Chao,WANG Cheng-fang and DU Shu-shan. Optimization of Extraction Process of Chongcao Anfei Tablet by Orthogonal Design[J]. China Journal of Experimental Traditional Medical Formulae, 2012, 18(8): 4-6 |
| |
| Authors: | WU Zhi-heng FEI Chao WANG Cheng-fang DU Shu-shan |
| |
| Affiliation: | 1.Department of Pharmacy,Affiliated Hospital of Medical College of Chinese People’s Armed Police Forces, Tianjin 300162,China;2 Protection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory,Beijing Normal University,Beijing 100875,China) |
| |
| Abstract: | Objective: To optimize extraction process of Chongcao Anfei tablet. Method: With yield of ephedrine hydrochloride as index, the amount of water,extraction time and extraction times was selected investigation factors,extraction technology of Chongcao Anfei tablet was optimized by orthogonal design. Result: Optimum extraction technology was as follows: 10,8,8 times the amount of water boiled 2,1,1 h. Conclusion: Optimized extraction technology was simple,feasible and met needs of large-scale production,it could provide references for further development of Chongcao Anfei tablet. |
| |
| Keywords: | Chongcao Anfei tablet extraction process orthogonal test ephedrine hydrochloride HPLC |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
|
点击此处可从《中国实验方剂学杂志》下载全文 |
|
