口腔粘膜早期鳞癌36例临床分析

36例口腔粘膜早期鳞癌的临床特征、治疗和预后分析结果表明:好发部位为舌缘、舌腹、颊和软腭等粘膜。损害最常表现为红色或红白间杂外表(占66.7％),很少发生溃疡和外突性生长,自觉症状不明显,容易漏诊。提示口腔粘膜的红白间杂损害可能是早期无症状鳞癌的最早指征,应全切活检以确诊。

Early Squamous Cell Carcinoma of the Oral Mucosa: a Clinical Analysis of 36 cases

The clinical features, treatment and prognosis of 36 cases of early oral squamous cell carcinoma are reported.It was found that higher proportion of these lesions were located in the lateral or ventral tongue, buccal mucosa and soft palate. Of 36 lesions, 24(66.7％) revealed erythroplakia(redness) or ery throplasia mixed with white components, whereas only 7 lesions (19.5％) were leukoplakia. The lesions showed so little ulcerating or Protruding growth that most of the patients didn't complain of any symptoms. We suggest that erythroplastic lesions or erythroplakia mixed with white components of oral mucosa appear to be the earliest visible sign of asymptomatic oral squamous cell carcinoma——invasive or in situ.The presence of white lesions appeared to be a little significant unless they were accompanied by eryth-ro plastic components. It is concluded that the persistence of erythroplastic lesions mixed with white components of oral mucosa, though no obvious symptom, should be completely excised for biopsy.