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少和/或弱精子症患者血浆同型半胱氨酸的测定及意义
引用本文:戈一峰,汪春晖,欧阳罗璇,邵永,姚兵,夏欣一,商学军,黄宇烽.少和/或弱精子症患者血浆同型半胱氨酸的测定及意义[J].中华男科学杂志,2008,14(12):1112-1114.
作者姓名:戈一峰  汪春晖  欧阳罗璇  邵永  姚兵  夏欣一  商学军  黄宇烽
作者单位:南京军区南京总医院解放军检验医学研究所男科研究室,江苏,南京,210002
摘    要:目的:检测少精子症和/或弱精子症患者空腹血浆同型半胱氨酸(homocysteine,Hcy)水平,并探讨其临床意义。方法:86例少精子症和/或弱精子症患者分为3组:少精子症组(n=21),弱精子症组(n=32),少弱精子症组(n=33);对照组(n=19)为精子密度及活力正常的健康男性精液。分别进行精液常规分析和空腹血浆同型半胱氨酸水平测定。结果:3组患者血浆Hcy水平均显著高于健康对照组(P<0.05),3组患者间血浆Hcy水平无显著性差异(P>0.05)。血浆中Hcy水平与3组患者的a级精子百分率、(a+b)级精子百分率及密度之间均呈负相关(r=-0.303、-0.339、-0.433,P<0.05)。结论:人血浆Hcy水平升高可能会直接或间接地影响精子发生,与少和/或弱精子症密切相关。

关 键 词:精子密度  精子活力  同型半胱氨酸

Determination of Plasma Homocysteine in Oligospermia and/or Asthenospermia Patients
GE Yi-feng,WANG Chun-hui,OUYANG Luo-xuan,SHAO Yong,YAO Bing,XIA Xin-yi,SHANG Xue-jun,HUANG Yu-feng.Determination of Plasma Homocysteine in Oligospermia and/or Asthenospermia Patients[J].National Journal of Andrology,2008,14(12):1112-1114.
Authors:GE Yi-feng  WANG Chun-hui  OUYANG Luo-xuan  SHAO Yong  YAO Bing  XIA Xin-yi  SHANG Xue-jun  HUANG Yu-feng
Institution:GE Yi-feng,WANG Chun-hui,OUYANG Luo-xuan,SHAO Yong,YAO Bing,XIA Xin-yi,SHANG Xue-jun,HUANG Yu-feng Department of ,rology,PLA Research Institute of Clinical Laboratory Medicine,Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu 210002,China
Abstract:Objective:To detect the level of fasting plasma homocysteine(Hcy) in patients with oligospermia and/or asthenospermia and to investigate its clinical significance.Methods:Semen quality analyses and fasting plasma Hcy determination were performed for 86 infertility patients(21 with oligospermia,32 with asthenospermia and 33 with oligo-asthenospermia) and 19 normal fertile volunteers.The results were compared.Results:The level of plasma Hcy was significantly higher in the infertility patients than in the norm...
Keywords:sperm concentration  sperm motility  homocysteine  
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