| 深静脉血栓患者血浆蛋白Z水平的研究 |
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| 引用本文： | 吴建平.深静脉血栓患者血浆蛋白Z水平的研究[J].浙江预防医学,2009,21(4). |
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| 作者姓名： | 吴建平 |
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| 作者单位： | 浙江大学医学院附属第一医院,浙江,杭州,310003 |
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| 摘 要： | 目的研究深静脉血栓(DVT)患者的血浆蛋白Z(PZ)水平,探讨DVT和PZ的相关性。方法采用酶联免疫吸附检测(ELISA)法测定68例DVT患者和55名健康人的蛋白Z水平;采用发色法测定蛋白C(PC),抗凝血酶(AT);采用凝固法测定蛋白S(PS)活性。结果DVT组PZ、PC、PS、AT水平分别为:PZ(1.31±0.60)mg/L,PC(123±25)%,PS(54±23)%,AT(114±17)%;健康对照组PZ、PC、PS、AT水平分别为:PZ(1.11±0.51)mg/L,PC(135±26)%,PS(68±17)%,AT(130±8)%。两组PZ水平无显著性差异(P>0.05);两组PC,PS,AT活性有显著性差异(P<0.05)。DVT组男性和女性PZ水平分别为(1.34±0.61)mg/L和(1.27±0.60)mg/L,健康对照组男性和女性PZ水平分别为(1.09±0.55)mg/L和(1.12±0.49)mg/L,不同性别之间PZ水平无显著性差异(P>0.05)。结论DVT患者和健康人的PC,PS和AT水平有显著性差异,DVT和PC,PS和AT水平具有相关性。DVT患者和健康人的PZ水平无显...
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| 关 键 词： | 深静脉血栓 蛋白Z 蛋白C 蛋白S 抗凝血酶 |
Study on Plasma Protein Z Level in Patients with Deep Venous Thrombosis |
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| WU Jian-ping.Study on Plasma Protein Z Level in Patients with Deep Venous Thrombosis[J].Zhejiang Journal of Preventive Medicine,2009,21(4). |
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| Authors: | WU Jian-ping |
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| Institution: | WU Jian-ping.The First Affiliated Hospital; Zhejiang University School of Medicine; Hangzhou; Zhejiang 310003; China; |
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| Abstract: | Objective To study the plasma protein Z(PZ) level in patients with deep venous thrombosis(DVT),and explore the relationship between PZ level and DVT.Methods Plasma PZ levels in 68 patients and 55 controls were measured by enzyme-linked immunosorbent assay(ELISA).Chro-kineti was used to detect the activity of protein C(PC) and antithrombin(AT) and coagulation method was used to determine the activity of protein S(PS).Results The levels of PZ,PC,PS and AT in DVT group were(1.31±0.60)mg/L,(123±25)%,(54±23)% an... |
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| Keywords: | Deep venous thrombosis Protein Z Protein C Protein S Antithrombin |
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