| 不同焦虑状态对糖尿病患者炎性因子及血管内皮功能的影响 |
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| 引用本文： | 秦敏丽,赵庆斌,王阿静.不同焦虑状态对糖尿病患者炎性因子及血管内皮功能的影响[J].昆明医学院学报,2014,35(6):101-103,107. |
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| 作者姓名： | 秦敏丽 赵庆斌 王阿静 |
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| 作者单位： | 秦敏丽 (潼关县人民医院内分泌科,陕西潼关,714399)； 赵庆斌 (西安交通大学医学院第一附属医院干三科,陕西西安,710061)； 王阿静 (西安交通大学医学院第一附属医院干三科,陕西西安,710061)； |
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| 基金项目： | 陕西省科技公攻基金资助项目(项目编号：2011K14-06-05) |
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| 摘 要： | 目的 探讨不同焦虑状态对糖尿病患者炎性因子及血管内皮功能影响.方法 选择糖尿病患者125例,采用汉密尔顿焦虑量表（HAMA）分为明显焦虑组、焦虑组及无焦虑组,每组分别有42、43、40例.入选后分别行IL-1 B IL-6、TNF-α及ET、IGF-1、VEGF检测.结果 焦虑组IL-6、TNF-α较无焦虑组,差异有统计学意义（P＜0.05）,明显焦虑组IL-1 β较无焦虑组,差异有统计学意义（P＜0.05）,IL-6、TNF-α较焦虑组及无焦虑组,差异有统计学意义（P＜0.05）.焦虑组ET、IGF-1、VEGF较无焦虑组,差异有统计学意义（P＜0.05）,明显焦虑组ET、IGF-1、VEGF较无焦虑组及焦虑组,差异有统计学意义（P＜0.05）.IL-6与IGF-1、VEGF呈相关性（P＜0.05）,TNF-α与ET呈负相关（P＜0.05）,与IGF-1、VEGF呈正相关（P＜0.05）.结论 焦虑状态可影响糖尿病患者炎性因子水平及血管内皮功能.
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| 关 键 词： | 糖尿病 焦虑 炎性因子 血管内皮 |
Evaluation of Inflammatory Factors and Vascular Endothelial Function in Patients with Diabetes and Different Anxiety Status |
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| QIN Min-li,ZHAO Qing-bin,WANG A-jing.Evaluation of Inflammatory Factors and Vascular Endothelial Function in Patients with Diabetes and Different Anxiety Status[J].Journal of Kunming Medical College,2014,35(6):101-103,107. |
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| Authors: | QIN Min-li ZHAO Qing-bin WANG A-jing |
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| Institution: | (Dept. of Endocrinology,People＇s Hospital of Tongguan County,Tongguan Shanxi 714399) ZHAO Qing-bin(Dept. of Cadre Care 3)The 1st Affiliated Hospital of Xi＇an Jiaotong University,Xi＇an Shanxi 710061,China) WANG A-jing(Dept. of Cadre Care 3)The 1st Affiliated Hospital of Xi＇an Jiaotong University,Xi＇an Shanxi 710061,China) |
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| Abstract: | Objective To investigate the different inflammatory factors and vascular endothelial function in patients with diabetes and different anxiety status.Methods 125 cases of diabetes using the Hamilton Anxiety Scale （HAMA） were divided into obvious anxiety group,anxiety group and without anxiety group,which were 42,43,40 cases.IL-1 β IL-6,TNF-α and ET,IGF-1,VEGF were evaluated.Results IL-6,TNF-α of anxiety group were significantly higher than those without anxiety （P＜0.05）,IL-1 β in the anxiety group was significantly higher than without anxiety group （P＜0.05）,IL-6,TNF-α showed significant difference with anxiety and without anxiety group.ET,IGF-1,VEGF of anxiety group showed significant difference with those without anxiety group （P＜0.05）,ET,IGF-1,VEGF of anxiety group showed significant differences with those without anxiety group （P＜0.05）.IL-6 and IGF-1,VEGF was significantly correlated （P＜0.05）,TNF-α and ET showed significant negative correlation （P＜0.05）,IGF-1,VEGF showed significant positive correlation （P＜0.05）.Conclusion Anxiety can affect levels of inflammatory factors and vascular endothelial function in patients with diabetes. |
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| Keywords: | Diabetes Anxiety Inflammatory factors Vascular endothelia |
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