成人间活体肝移植体会：附3例报告

目的总结和分析成人间活体肝移植(LDLT)的临床经验。方法对2007年2月—2007年7月的3例成人间活体肝移植的临床资料进行回顾性分析。结果供体为供体右半肝(不带肝中静脉)1例,供体扩大左半肝(带肝中静脉、尾状叶)2例,GV/SLV均≥40%。3对供者及患者术后均恢复良好,无小肝综合征发生,均未出现严重并发症。术后左半肝供者较右半肝供者肝功能恢复更快。结论如左半肝GV/SLV≥40%,可优先选择左半肝作为供肝;胆道重建不必放置胆管引流管;成人间LDLT是治疗终末期肝病的安全有效的手段。

Adult-to-adult living donor liver transplantation: report of 3 cases

Objective To evaluate the clinical application of adult-to-adult living donor liver transplantation(A-A LDLT).Methods The clinical data of 3 cases of A-A LDLT performed in our hospital between February 2007 and July 2007 were retrospectively analyzed.Results Of the three grafts,1 case was a right lobe graft(not including the middle hepatic vein),and 2 cases were left lobe grafts(including the middle hepatic vein and caudate lobe).GV/SLV were all more than 40%.The 3 pairs of recipients and donors recovered uneventfully.No small-for-size syndrome or severe complications occurred.The recovery of hepatic function of left lobe donors was faster than that of the right lobe donor.Conclusions If GV/SLV of left lobe graft is more than 40%,the left lobe living donor should be preferably selected.There is no need for placement of drainage tube when the bile duct is reconstructed.A-A LDLT is a safe and effective procedure for treatment of end-stage liver diseases.