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| 唑来膦酸治疗骨转移癌疼痛临床观察 | |
| 引用本文： | 王潞,叶晓兵,吴跃文,陈意红,陈方满. 唑来膦酸治疗骨转移癌疼痛临床观察[J]. 皖南医学院学报, 2006, 25(3): 180-182 |
| 作者姓名： | 王潞 叶晓兵 吴跃文 陈意红 陈方满 |
| 作者单位： | 1. 皖南医学院附属弋矶山医院,肿瘤内科,安徽,芜湖,241001 2. 皖南医学院附属弋矶山医院,放疗科,安徽,芜湖,241001 3. 皖南医学院附属弋矶山医院,放射科,安徽,芜湖,241001 |
| 摘 要： | 目的:评价国产唑来膦酸治疗恶性肿瘤骨转移疼痛的疗效和安全性。方法:恶性肿瘤骨转移患者42例,随机分配至试验组和对照组各21例分别给予唑来膦酸4 mg与帕米膦酸二钠90 mg静滴,观察其疗效和不良反应。结果:试验组20例总缓解率为90%,对照组21例总缓解率85.7%,不良反应发生率分别为40%和47.6%,两组差异均无统计学意义(P>0.05)。结论:国产唑来膦酸治疗恶性肿瘤骨转移疼痛疗效显著,安全可靠。 |
| 关 键 词： | 唑来膦酸 帕米膦酸二钠 骨转移癌 骨痛 |
| 文章编号： | 1002-0217(2006)03-0180-03 |
| 收稿时间： | 2006-02-23 |
| 修稿时间： | 2006-02-23 |
Clinical observation of zometa for pain relief in metastatic bone cancer |
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| WANG Lu,YE Xiao-bin,WU Yue-wen,CHEN Yi-hong,CHEN Fang-man. Clinical observation of zometa for pain relief in metastatic bone cancer[J]. Acta Academiae Medicinae Wannan, 2006, 25(3): 180-182 | |
| Authors: | WANG Lu YE Xiao-bin WU Yue-wen CHEN Yi-hong CHEN Fang-man |
| Affiliation: | Department of Oncology, Yijishan Hospital, Wannan Medical College , Wuhu 241001 ,China |
| Abstract: | Objective:To evaluate the safety and efficacy of zometa(made in China) in relieving the pain from metastatic bone cancer.Methods: 42 cases of metastatic bone cancer patients were randomized into test group and control group.The two groups were treated intravenously with zometa in a dosage of 4 mg and pamidronate 90 mg,respectively.Therapeutic effectiveness was evaluated and side effects were recorded as well.Results: 90%(20 of 42) in test group and 87.5%(21 of 42) in control group got relieved after the treatment.No significant difference was observed between the two groups.The incidence of side effect was 40% in test group and 47.6% in control group with on significant difference between the two groups.Conclusion: Zometa made in china is effective and safe to relieve pain from metastatic bone cancer. |
| Keywords: | zometa pamidronate metastatic bone cancer bone pain |
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