某部新兵乙肝感染状况和乙肝疫苗接种效果观察

目的调查某部新兵的乙型肝炎病毒(HBV)感染状况和疫苗接种效果。方法采用整群抽样方法抽取630名新兵,进行统一的流行病学调查,采用ELISA方法检测HBV-M,对HBV-M全阴者接种乙肝疫苗,按0、2程序,剂量20μg,接种2月后检测抗体水平。结果该部队新兵中HBsAg阳性3人(0.5%);抗HBs阳性390人(61.9%),抗HBs阴性240人(38.1%),抗HBe和(或)抗HBc阳性28人(4.4%),60名接种乙肝疫苗的新兵中,57人检测HBV-M,抗HBs阳性49人(85.96%)。结论该部队新兵HBV现症感染率远远低于我国普通人群平均感染率,对HBV-M阴性新兵接种乙肝疫苗,按0、2程序,剂量20μg效果较为理想。

Observation on status of hepatitis B infection and the effect of hepatitis B vaccine in recruits of a certain army

Objective To investigate the status of hepatitis B infection and the effect of hepatitis B vaccine in recruits of a certain army. Methods Determined the unit's survey of 630 recruits by cluster sampling and conducted a unified epidemiological survey.Serum HBV marker(HBV-M) was tested by ELISA.To those who were all HBV-M negative,gave 20μg HBV vaccine according to 0,2 programs and tested the antibody level after 2 months. Results Among all survey,the number of recruits with HBsAg positive,anti-HBs positive and anti-HBs negative were 3(0.5%),390(61.9%) and 240(38.1%) respectively.The number of recruits with anti-HBe and/or anti-HBc positive was 28(4.4%).57 recruits tested their serum HBV-M among the 60 recruits who got the injection of HBV vaccine and 49(85.96%) engendered anti-HBs. Conclusion The present HBV infection rate among the recruits in this army is far lower than the average HBV infection rate among common population.Giving 20μg HBV vaccine according to 0,2 programs had good immune effect on the recruits who were HBV-M negative.