Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode |
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| Authors: | Ir. N. J. M. Rijkhoff J. Holsheimer F. M. J. Debruyne H. Wijkstra |
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| Affiliation: | (1) Present address: Department of Urology, University Hospital Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands;(2) Biomedical Engineering Division, Department of Electrical Engineering, University of Twente, The Netherlands |
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| Abstract: | The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode. |
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| Keywords: | Electrical nerve stimulation Modelling Selective small fibre activation |
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