| 海藻低聚糖对放射损伤的防护作用研究 |
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| 引用本文： | 王海青,李翊.海藻低聚糖对放射损伤的防护作用研究[J].中国辐射卫生,2009,18(1):33-35. |
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| 作者姓名： | 王海青 李翊 |
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| 作者单位： | 解放军第401医院肿瘤中心, 山东青岛 266071 |
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| 摘 要： | 目的 探讨海藻低聚糖对受6.0GyX射线照射小鼠的辐射防护作用。方法 采用6MVX直线加速器一次全身照射小鼠,3个海藻低聚糖组照射后给药15d。观察小鼠30d存活率、小鼠外周血白细胞总数和红细胞数,脾脏指数,全血谷胱甘肽过氧化物酶(GSH-Px)活力,血清超氧化物歧化酶(SOD)活力。结果 海藻低聚糖能加速小鼠外周血白细胞和红细胞数的恢复,明显提高脾脏指数,并且可引起抗氧化物酶GSH-Px和SOD活性显著增高。结论 海藻低聚糖对受照射小鼠有明显的辐射防护作用。
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| 关 键 词： | 海藻低聚糖 辐射保护 生存率 白细胞总数 抗氧化 |
| 收稿时间： | 2008-07-24 |
Radioprotective Effect of the Seaweed Polysaccharides with Low Molecular Weights on the Mice Injured by Irradiaton |
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| WANG Hai-qing,LI Yi.Radioprotective Effect of the Seaweed Polysaccharides with Low Molecular Weights on the Mice Injured by Irradiaton[J].Chinese Journal of Radiological Health,2009,18(1):33-35. |
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| Authors: | WANG Hai-qing LI Yi |
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| Institution: | 401.Hospital of PLA, Qingdao 266071 China |
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| Abstract: | Objective To study the radioprotection effect of the seaweed polysaccharides with low molecular weights on irradiated mice.Methods The seaweed polysaccharides with low molecular weights are applied to mice irradiated with 6.0 Gy rays.15days after the irradiation,variations in counts of peripheral white blood cell and erythrocytes,spleen index,activities of the GSH-Px and SOD were studied.Results The seaweed polysaccharides with low molecular weights significantly promoted recovery of peripheral white blood ... |
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| Keywords: | Seaweed polysaccharide with low molecular weight Radioprotective effect Peripheral white blood cell Antioxidation effect |
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