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Herpes zoster in patients with polymyositis and dermatomyositis
Authors:S Nagaoka  K Tani  Y Ishigatsubo  J Chiba  K Kato  K Matsunaga  M Narita  T Igarashi  T Okubo
Affiliation:First Department of Internal Medicine, Yokohama City University, School of Medicine.
Abstract:Twenty-two patients with polymyositis and dermatomyositis (PM-DM) were retrospectively studied with regard to development of herpes zoster. Herpes zoster occurred with high frequency in patients with PM-DM. The clinical courses of zoster infections were uneventful; no severe complications nor deaths occurred, and only one patient had post-therapeutic neuralgia. No specific therapy for this infection was necessary. Zoster tended to occur in the inactive stage of PM-DM. PM-DM patients with herpes zoster had a significantly higher incidence of antinuclear antibody. There seemed to be no relationship between steroid therapy and herpes zoster infection.
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