| 微小RNA与乳腺癌细胞的增殖和转移 |
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| 引用本文： | 陈晓兰,秦树佩,杨建新.微小RNA与乳腺癌细胞的增殖和转移[J].国际肿瘤学杂志,2012,39(4):265-268. |
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| 作者姓名： | 陈晓兰 秦树佩 杨建新 |
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| 作者单位： | 广东药学院附属第一医院肿瘤科, 广州,510310 |
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| 基金项目： | 中山市科技计划项目（20083A186） |
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| 摘 要： | 乳腺癌的发生是一个多因素参与的阶段性演进过程，微小RNA（miRNA）可通过调节肿瘤细胞的增殖、凋亡和迁移参与肿瘤发生、发展及远处浸润转移。miRNA影响乳腺癌细胞的增殖与转移机制研究将为乳腺癌的诊治提供新的思路。
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| 关 键 词： | 微RNAs 乳腺肿瘤 细胞增殖 肿瘤转移 |
MiRNA and the proliferation and metastasis of breast cancer cells |
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| CHEN Xiao-lan
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QIN Shu-pei
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YANG Jian-xin.MiRNA and the proliferation and metastasis of breast cancer cells[J].Journal of International Oncology,2012,39(4):265-268. |
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| Authors: | CHEN Xiao-lan QIN Shu-pei YANG Jian-xin |
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| Institution: | Department of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510310, China |
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| Abstract: | The tumorigenesis of breast cancer is a multistep process with many factors. The microRNAs (miRNA) participates in the development and distance metastasis of tumor by regulating proliferation, apoptosis and migration of tumor cells. The study of the mechanisms that miRNA impacting breast cancer cell proliferation and metastasis may provide new ideas for the diagnosis and treatment of breast cancer. |
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| Keywords: | MicroRNAs Breast neoplasms Cell proliferation Neoplasm metastasis |
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