| 乳腺癌患者手术治疗前后血清CA15-3、CA50和M-CSF检测的临床意义 |
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| 引用本文： | 王艳召. 乳腺癌患者手术治疗前后血清CA15-3、CA50和M-CSF检测的临床意义[J]. 放射免疫学杂志, 2012, 25(1): 14-15 |
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| 作者姓名： | 王艳召 |
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| 作者单位： | 江苏省丰县人民医院,221700 |
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| 摘 要： | 目的:探讨了乳腺癌患者手术治疗前后血清CA15-3、CA50和M-CSF水平的变化及临床意义。方法:应用放射免疫分析对32例乳腺癌患者进行了手术治疗前后血清CA15-3、CA50和M-CSF检测,并与35名正常健康人作比较。结果:乳腺癌患者在手术治疗前血清CA15-3、CA50和M-CSF水平均非常显著地高于正常人组(P<0.01),经手术治疗6个月后则与正常人组比较无显著性差异(P>0.05)。结论:检测血清CA15-3、CA50、M-CSF水平的变化对乳腺癌的诊断、治疗和预后观察均具有重要的临床价值。
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| 关 键 词： | 乳腺癌 糖类抗原15-3(CA15-3) 糖类抗原-50(CA50) 巨噬细胞刺激因子(M-CSF) |
Clinical Relevance of Changes on Serum CA15-3,CA50 and M-CSF Levels After Operation in Patients with Breast Cancer |
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| Wang Yan-zhao. Clinical Relevance of Changes on Serum CA15-3,CA50 and M-CSF Levels After Operation in Patients with Breast Cancer[J]. Journal of Radioimmanology, 2012, 25(1): 14-15 |
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| Authors: | Wang Yan-zhao |
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| Affiliation: | Wang Yan-zhao Jiangsu Fong County People＇s Hospital, Jiangsu( 221700), China |
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| Abstract: | Objective To explore the clinical significance of changes on serum CA15-3, CASO and M-CSF levels after surgery in patients with breast cancer. Methods Serum CA15-3, CASO and M-CSF concentration from patients with breast cancer and healthy normal controls were determined by RIA. Results Before operation, the serum CA15-3 ,CA.50 and M-CSF levels in the patients with breast cancer were significantly higher than those in controls （P 〈 0. 01 ）, after surgery for 6 months , the serum CA15-3, CASO and MCSF levels in the patients were no significant difference from those in controls （P 〉 0. 05）. Conclusion Detection of serum CA15-3, CAS0 and M-CSF levels after operation might be of prognostic importance in patients with breast cancer. |
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| Keywords: | breast cancer carbohydrate antigen-15-3 （ CA15-3 ） carbohydrate antigen-50 （ CASO） macrophage colomy-stimula- ting factor （M-CSF） |
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