亚健康状态三级干预方案的临床随机对照试验

目的 探讨亚健康状态的三级干预方案的临床疗效及二级与三级干预方案临床疗效的差异.方法 通过对公务员的亚健康状态流行病学调查,随机选取116例被判断为亚健康状态者为观察组,剔除不合移病例者进行三级干预;另随机选取64例为对照组,剔除不合移病例者直接进行亚健康状态一级和二级干预.结果 观察组给予三级干预方案后,临床痊愈54例,显效42例,有效8例,无效7例,总有效率为93.69%;对照组给予二级干预方案后,临床痊愈7例,显效10例,有效17例,无效26例,总有效率为56.67%.两组比较差异有统计学意义(2=60.232,P<0.01);两组干预前后症状积分差异比较差异有统计学意义(P<0.01).结论 公务员亚健康状态三级干预方案的临床疗效优于二级干预方案.亚健康状态三级干预方案对于公务员亚健康状态具有显著的临床疗效,可以应用于亚健康状态的防治.

The randomized controlled trial on the three staged protocol for sub-health intervention

Objective To evaluate the efficacy and the applicability of three-staged protocol on intervention of sub-health. Methods Epidemical investigation on sub-health was carried out among the civil service staffs.One hundred and sixteen staffs that were confirmed in sub-health were randomly assigned into the trial group undergoing the tertiary intervention.Another 64 random staffs were assigned into the control group receiving primary or secondary intervention. Results In the trial group,Full recovery,marked effective,effective and null were observed in 54,42,8 and 7 cases,respectively,with significant rate of 93.69% in trial group;while in 7,10,17 and 26 cases,respectively,with significant rate of 56.67% in control group.There was significant difference revealed between the two groups according to chi-square test(χ2=60.232,P<0.01).According to one-way ANOVA,there were significant improvement in the both groups(P<0.01). Conclusion The clinical efficacy of the tertiary protocol for intervening sub-health was superior to the secondary protocol among the civil service staffs.