Phosphatidylserine activity on prolactin brain receptors of aged rabbits期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Phosphatidylserine activity on prolactin brain receptors of aged rabbits

Authors:	Raffaele Di Carlo Giampiero Muccioli Corrado Ghe' Giuseppina Bellussi Delia Ravetti Enrico Genazzani

Affiliation:	¹ Department of Experimental Pharmacology, University of Naples, Italy ² Institute of Pharmacology, University of Turin, Italy

Abstract:	1. 1. PRL receptors in the hypothalamus and substantia nigra of aged rabbits (28-month-old) are significantly reduced in comparison with young rabbits (6-month-old). 2. 2. Repeated treatments with BC-PS are able to gradually increase the PRL receptor number both in hypothalamus and nigra. However only after 30 days of treatment the binding reaches the mean values observed in young rabbits. 3. 3. Aged rabbits showed an evident increase in PRL plasma levels in comparison with young animals. In BC-PS treated animals this increase was not more apparent. Moreover in young rabbits treated with BC-PS an evident decrease in basal PRL plasma levels was observed. Author Keywords: aging; brain; phosphatidylserine; prolactin; prolactin receptors

Keywords:	aging brain phosphatidylserine prolactin prolactin receptors
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