子宫乳头状浆液性癌临床病理分析及治疗探讨

目的通过对子宫乳头状浆液性癌的临床病理特征的分析，探讨其合理的治疗方法。方法自1983年1月至1998年6月，我院收治子宫乳头状浆液性癌16例，对其临床病理、治疗及预后进行回顾性研究。结果全部病例采用手术治疗，术后辅助放疗和/或化疗者14例。56.2%的病例肌层浸润深度超过1/2肌层(9/16)，62.5%有宫外扩散(10/16)，淋巴结转移率62.5%(5/8)，几乎缺乏雌、孕激素受体。预后差，随访期内9例死亡。结论子宫乳头状浆液性癌有其独特的临床病理特征，与普通的子宫内膜癌明显不同，合理的个体化综合治疗可延长生存期。

Clinico-pathologicfeatures and treatment of uterine papilla ry serous carcinoma

Objective To study the rational therapy for uterine papillary serous carcinoma(UPSC)and analyze its clinico pathologic features.Methods Sixteen cases of UPSC were treated in our hospital between January 1,1983 and June 30,1998.The clinico pathologic features,treatment methods and prognosis were retrospectively analyzed.Results All the patients underwent operation,fourteen of them received radiotherapy and /or postoperative chemotherapy.Deep myometrial invasion occured in 56.2% of the cases (9/19).62.5% had extrauterine disease(10/16).The rate of lymph node metastasis was 62.5%(5/8).Estrogen or progestin receptors were rarely seen. Nine of the sixteen died during the follow up period,indicating poor prognosis.Conclusions The clinico pathologic features of UPSC are different from the common endometrial carcinoma.Rationally individualized treatment can lengthen survival time. [