丙泊酚和芬太尼复合静脉麻醉在前列腺穿刺活检中的应用

目的:探讨经直肠前列腺穿刺活检引起的疼痛情况,评价丙泊酚和芬太尼静脉麻醉的镇痛效果及安全性。方法:经直肠行前列腺10针穿刺活检患者60例,随机分三组,每组20例。A组为单纯丙泊酚组:静脉注射丙泊酚2mg/kg,B组为芬太尼+丙泊酚组:先静脉注射芬太尼1μg/kg,1min后静注丙泊酚1.5mg/kg,C组为生理盐水组:静脉注射生理盐水5ml。对患者术中生命体征监测和术中及术后1h内的疼痛行视觉模拟评分尺评分。结果:A、B、C组术中疼痛评分分别为0、0、4.5±1.8;术后1h疼痛评分分别为2.7±1.1、2.5±1.0、2.8±1.3。静脉复合麻醉对血压、心率和呼吸轻度影响,在安全范围或吸氧能纠正。结论:应用丙泊酚和芬太尼静脉复合麻醉明显减轻患者在前列腺穿刺活检术中疼痛,是一种安全、有效的麻醉方法,值得临床推广应用。

Efficacy and safety of intravenous anesthesia for prostate biopsy by propofol and fentanyl injection guided by transrectal ultrasound

Objective To describe the condition of the pain during and after transrectal ultrasound-guided prostate biopsy and assess the safety and efficacy of intravenous anesthesia with propofol and fentanyl for pain control.Mothods Sixty consecutive patients were divided into 3 groups randomly, with 20 patients each group, sign during biopsy and record the pain changes intraoperative and postoperative （10-piont visual analog score）.Results The pain score during this procedure was 0, 0, 4.5 ± 1.8 in group A, B and C. The pain score lh after biopsy was 2.7 ± 1.1,2.5 ± 1.0, 2.8 ±1.3. Intravenous anesthesia affect the patients BP, HR and R lightly.Conclusions The pain caused by biopsy is obvious,propofol and fentanyl together intravenous anesthesia can release the pain, it is a safe and effective.