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| CD3AK细胞肝瘤内注射结合TACE治疗中晚期原发性肝癌的近期疗效观察 | |
| 引用本文： | 徐永茂,张国龙,张南征,刘军权,邓凯莉,史跃.CD3AK细胞肝瘤内注射结合TACE治疗中晚期原发性肝癌的近期疗效观察[J].中国肿瘤临床,2002,29(1):27-30. |
| 作者姓名： | 徐永茂 张国龙 张南征 刘军权 邓凯莉 史跃 |
| 作者单位： | 1. 解放军第九七医院消化肿瘤科,江苏省徐州市,221004 2. 解放军第九七医院实验科,江苏省徐州市,221004 3. 解放军第九七医院特诊科,江苏省徐州市,221004 4. 解放军第九七医院放射科,江苏省徐州市,221004 |
| 摘 要： | 目的：观察CD3AK细胞肝瘤内局部注射结合肝动脉插管化疗栓塞术（TACE）治疗中、晚期原发性肝癌的近期观察疗效。方法：对20例中、晚期原发性肝癌的外周血行CD3AK细胞培养后肝瘤内局部注射并结合肝动脉插管化疗栓塞术，并与同期24例中、晚期原发性肝癌单纯行肝动脉插管化疗栓塞术（TACE）相对照。结果：完全缓解（CR）1例，部分缓解（PR）15例，有效率RR（CR＋PR）80．0％，患者的细胞免疫功能明显提高（P＜0．01）。结论：CD3AK细胞局部注射结合化疗治疗中、晚期恶性肿瘤的近期疗效增加（P＜0．05），患者的细胞免疫功能明显提高，值得临床推广和应用。 |
| 关 键 词： | CD3AK细胞 局部注射 肝癌 TACE 化疗 |
| 文章编号： | 1000-8179(2002)01-0027-04 |
| 修稿时间： | 2001年3月21日 |
Short-Term Effect of Intra-Hepatic Tumor Injection of CD3AK Cells Combined with TACE for Advanced Primary Hepatic Cancer |
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| Xu Yongmao Zhang Guolong Zhang Nanzheng et al G-I,Oncologic.Short-Term Effect of Intra-Hepatic Tumor Injection of CD3AK Cells Combined with TACE for Advanced Primary Hepatic Cancer[J].Chinese Journal of Clinical Oncology,2002,29(1):27-30. | |
| Authors: | Xu Yongmao Zhang Guolong Zhang Nanzheng G-I Oncologic |
| Institution: | Xu Yongmao Zhang Guolong Zhang Nanzheng et al G-I Oncologic Department,The97Hospital of PLA,Xuzhou City |
| Abstract: | Objective:To observe the therapeutic effect of intra-tumor injection of CD 3 AK cells combined with transcatheter hepatic arterial chemoembolization(TACE)for medium and ad-vanced hepatic cancers.Methods:Twenty patients with primary medium and advanced hepatic cancers(PHC)were treated by CD 3 AK local injection combined with TACE(treated group)and it was compared with24patients only treated with TACE(control group).Results:The results showed that CR1patient,PR15patients.The effective rate of the treated group was80%and the immunity function improved obviously.(P<0.01).Conclusion:The intra-tumor injection of CD 3 AK cells combined with TACE can enhance the short-term curative effect and improve the immunity functions of the patients with advanced PHC. |
| Keywords: | CD 3 AK cell Local injection Treatment Medium and advanced hepatic cancer |
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